1,8-Naphthyridine, 2-broMo- - Names and Identifiers
1,8-Naphthyridine, 2-broMo- - Physico-chemical Properties
Molecular Formula | C8H5BrN2
|
Molar Mass | 209.04 |
Density | 1.656 |
Melting Point | 152-153 °C |
Boling Point | 307 °C |
Flash Point | 140 °C |
Vapor Presure | 0.00132mmHg at 25°C |
pKa | 2.00±0.30(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.685 |
1,8-Naphthyridine, 2-broMo- - Introduction
2-Bromo-1, 8-naphythyridine is an organic compound with the chemical formula C10H6BrN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Bromo-1,8-naphthyridine is a white solid.
-Melting point: Its melting point range is 96-97°C.
-Boiling point: Its boiling point is about 366°C.
-Solubility: It is soluble in organic solvents such as ether and methanol, but almost insoluble in water.
Use:
- 2-Bromo-1,8-naphthyridine is widely used in organic synthesis. It can be used as an intermediate, as a starting material or as a reaction intermediate in the synthesis of other organic compounds.
-In drug development, 2-Bromo-1,8-naphthyridine can be used to synthesize pharmaceutical compounds, such as antibiotics.
Preparation Method:
The preparation method of -2-Bromo-1,8-naphthyridine can be obtained by reacting 2-bromo-8-hydroxynaphthalene with pyridine. The reaction conditions can be a longer reaction time at a certain temperature, adding an appropriate organic solvent and catalyst.
Safety Information:
- 2-Bromo-1,8-naphthyridine is an organic bromine compound and is a potentially dangerous chemical substance. During use, appropriate laboratory safety measures should be taken, such as wearing protective glasses, gloves and laboratory coats.
-Due to the lack of specific toxicity data, general chemical handling and storage practices should be followed when using. It is important for those who use it to understand its toxicity, danger and proper handling.
-When using or disposing of 2-Bromo-1,8-naphthyridine, relevant national and regional laws and regulations should be observed to ensure its correct management and handling.
Please note that this information provides a general overview and should be carefully reviewed in the literature or consulted with a professional.
Last Update:2024-04-09 19:05:51